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Chem12A
Lecture Course Review Fall'01
Chemistry
links
Click
above for Access Handouts
Chime Models
These models are listed by experiment and
include reactants, products, intermediates, and in some cases solvents.
You need the Chime
plug-in from MDL to view these models
Chem 12 BL (Welcome Back!)
Experiment 32,33,34
Benzaldehyde
Thiamine
Benzoin
Benzil
Potassium Benzilate
Benzilic
Acid
Question 5 - Concerning Alterations
of Procedure In The Presence of an Enzyme
For this question you may want to turn to 25.4
in Ege, specifically page 1009. Here you will find a definition
of the term Denature, as it applies to proteins. Denaturing
a protein is defined as changing its structure to a form
which is biologically inactive. If you take a look at the representation
of an enzyme in the essay proceeding experiment 32,
you will see the intricate shape of a protein. This shape is responsible
for the enzyme's catalytic property.
This intricate shape also allows a biological enzyme to catalyze a
reaction with highly specific products with
specific connectivity and stereochemistry. The description on page
1009 lists the 3 major ways a protein can be denatured.
Experiment 31A
Bromobenzene
Phenylmagnesium
bromide
Benzophenone
Triphenylmethanol
Question 5 C- Formation of a
carboxylic acid using a Grignard Reagent
For this question take a glance at the main reaction
in Experiment 31B
More information on this reaction can be found in your lecture text
in 14.3 on the bottom of
pg. 561 - Reactions of Organometallic Reagents with Carbon Dioxide
Macrocale Extraction of Piperine
Piperine
- (E,E) form from black pepper
Experiment 30
(+)
Tartaric Acid
R(+)-
Phenylethylamine
S(-)-
Phenylethylamine
Question 6- Draw the S enantomer
of the amine
If there is one question that this site can help
you with it's this one.
Simply view the S enantomer and use a
stick
and wedge diagram to describe what you see. If you wish you can
also use a Fisher diagram. The Fisher projection
is probably the most desired method.
Chem 12AL
Experiment 12A
2-methylbutyl
acetate
Dehydration & GC
2-methylcyclohexanol
1-methylcyclohexene
3-methylcyclohexene
SN Kinetics
2-propanol
t-butylchloride
t-butylcarbocation
t-butanol
isobutene
isopropyl-t-butylether
!?Problem Set?! (Question
2-C)
Did you construct a model of Allyl
Bromide and still have no idea why the conformation
that allows for an E2 reaction
to occur is unstable? Well your models don't show the actual
volume that the atoms displace.
If you take a look at Allyl
Bromide using the ball&stick representation,
which is much like the models from
your model kit, and then look at it with Van der Waals radii the
problem becomes much clearer. The
conformation is extremely high energy due to steric effects between the
Bromide and the hydrogen attached
to the #1Carbon. Take
a look. Also the resulting C=C=C product
is very unstable. The Hydrogen
used to create the double bond is not likely to be removed because it is
attached
to a vinyl carbon with sp2 hybridized
orbitals.
Kinetic and Equilibrium Control
Semicarbazide
Cyclohexanone
2-Furaldehyde
Cyclohexanone
Semicarbazone
2-Furaldehyde
Semicarbazone
Acid/Base Extraction
Benzoic
Acid
Benzoate
2-naphthol
2-naphthoxide
1,4-dimethoxybenzene
IR Spectroscopy
Intro
to IR Spectroscopy
a resource that nicely compliments Chapter 11 in Ege and Tech 19 in
PLKE
There is a protocol for deciphering IR spectra as well as exercises.
IR WIZARD!!!!!!
A must try!!!! Enter a wave number into IR Wizard and it will retrieve
possible groups.
Good Luck
Spearmint and Caraway Oil
R-(-)-
Carvone
From Spearmint Oil
S-(+)-
Carvone
From Caraway Oil